• News
  • Film and TV
  • Music
  • Tech
  • Features
  • Celebrity
  • Politics
  • Weird
  • Community
  • Advertise
  • Terms
  • Privacy & Cookies
  • LADbible Group
  • LADbible
  • SPORTbible
  • GAMINGbible
  • Tyla
  • UNILAD Tech
  • FOODbible
  • License Our Content
  • About Us & Contact
  • Jobs
  • Latest
  • Topics A-Z
  • Authors
Facebook
Instagram
X
Threads
TikTok
YouTube
Submit Your Content
Christina Applegate details side effect of MS that stopped her from looking in the mirror for a year

Home> Celebrity> News

Published 16:52 3 Mar 2026 GMT

Christina Applegate details side effect of MS that stopped her from looking in the mirror for a year

Applegate was diagnosed with Multiple Sclerosis in 2021

Britt Jones

Britt Jones

google discoverFollow us on Google Discover

Christina Applegate has opened up one element of living with multiple sclerosis (MS) that stopped her from being able to look at herself.

The actor first opened up about her health struggles when she revealed in an X post in 2021, that read: "It's been a strange journey. But I have been so supported by people that I know who also have this condition.

"It’s been a tough road. But as we all know, the road keeps going. Unless some a**hole blocks it."

MS is an incurable chronic condition that impacts the spinal cord and nervous system, among other parts of the body, making it hard for people with it to function normally during their day-to-day routine.

Advert

According to the Mayo Clinic, symptoms of MS include problems with vision, arm or leg movements, sensation or balance, numbness, muscle stiffness, and also with thinking, learning and planning.

Christina Applegate was diagnosed with MS in 2021 (Photo by Gilbert Flores/Variety via Getty Images)
Christina Applegate was diagnosed with MS in 2021 (Photo by Gilbert Flores/Variety via Getty Images)

Applegate explained that because of her symptoms, she is largely confined to her bed, per her talk with People.

But through it all, there was a surprising side effect of her MS that had Applegate unable to look in the mirror, or even watch her performance in Dead to Me.

In a recent interview, the 51-year-old told The Los Angeles Times that after season three was released, she didn’t watch it until months later because she doesn’t like ‘seeing myself struggling’.

However, there’s another reason.

She said: "Also, I gained 40 lbs. because of inactivity and medications, and I didn't look like myself, and I didn't feel like myself."

However, she revealed that she was ‘able to distance myself from my own ego, and realize what a beautiful piece of television it was’ and enjoy the scenes she wasn’t part of, calling them 'so much fun to see and experience for the very first time.’

Applegate said she couldn't look in the mirror for a year (Photo by VALERIE MACON/AFP via Getty Images)
Applegate said she couldn't look in the mirror for a year (Photo by VALERIE MACON/AFP via Getty Images)

She added of her career: "It's my last awards show as an actor probably, so it's kind of a big deal.

"Right now, I couldn't imagine getting up at 5 a.m. and spending 12 to 14 hours on a set; I don't have that in me at this moment."

According to Yahoo! she also struggled with her Hollywood Walk of Fame ceremony in 2022, explaining: "I want to throw up when I think of the pictures that are out there of me. I look sad and embarrassed. Because all I can think is: Everyone is staring. Once people stared at my b****. But now I knew they were staring not only because I was disabled; they were staring because I was fat, forever an unacceptable fate for women in Hollywood."

She continued: "Sometimes the weight bothered me more than the disease. I didn't look in the mirror for a year."

Applegate has long spoken about the struggles she has endured with MS, explaining on the Let's Talk Off Camera with Kelly Ripa podcast last year that it was her daughter Sadie that was keeping her going.

"I don't get up in the morning with that, I get up because of her. She's the reason I'm still here and trying," she admitted.

She added: "But she did say to me, and we got into a big thing the other day, and sorry Sadie, but it has to be said. She said, 'I missed who you were before you got sick'.

"That is just like a knife to the heart because I miss who I was before I got sick too. Very much."

In her new memoir, titled You With The Sad Eyes, the actress also revealed that her ‘dedication to life’ is Sadie.

Featured Image Credit: John Salangsang/Variety/Penske Media via Getty Images

Topics: Health, Christina Applegate, Celebrity

Britt Jones
Britt Jones

Advert

Advert

Advert

Choose your content:

2 hours ago
3 hours ago
  • Armchair Expert with Dax Shepard
    2 hours ago

    Dax Shepard opens up on his childhood sexual abuse that he's putting in his memoir

    Dax Shepard has said it took him months to write this part of his memoir

    Celebrity
  • Frazer Harrison/WireImage/Getty
    2 hours ago

    Harrison Ford shares important rule that is the success behind his 15-year marriage

    The Indiana Jones actor received the SAG-AFTRA's annual Lifetime Achievement Award on Sunday

    Celebrity
  • Richard Corkery/NY Daily News Archive via Getty Images/John Nacion/WireImage via Getty Images
    2 hours ago

    JFK's grandson slams Ryan Murphy's 'grotesque' new series centred on late uncle's relationship

    The Hulu series released on the streaming platform last month

    Celebrity
  • Steve Granitz/FilmMagic
    3 hours ago

    Justin Timberlake petitions court to stop DUI video footage going public

    Timberlake was in the middle of his 2024 tour when he was pulled over by police

    Celebrity
  • Christina Applegate opens up on multiple sclerosis diagnosis reality as she reveals she's mostly confined to her bed
  • Christina Applegate reveals how her MS diagnosis has ‘broken’ her 14-year-old daughter Sadie
  • Christina Applegate opens up about being hospitalized over 30 times with ‘unimaginable’ pain following MS diagnosis
  • Christina Applegate shares devastating reason she gets up in the morning following MS diagnosis