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    Christina Applegate shares devastating reason she gets up in the morning following MS diagnosis

    Home> Celebrity> News

    Published 10:19 31 Jul 2025 GMT+1

    Christina Applegate shares devastating reason she gets up in the morning following MS diagnosis

    Christina Applegate has been speaking about about live with MS

    Callum Jones

    Callum Jones

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    Christina Applegate has detailed the devastating reason she gets up in the morning following an MS diagnosis.

    The 53-year-old first opened up on her health issues in 2021, revealing that she had been diagnosed with multiple sclerosis (MS).

    Taking to X, formerly known as Twitter, at the time, the Bad Moms and Married…With Children actor said: "It's been a strange journey. But I have been so supported by people that I know who also have this condition.

    "It’s been a tough road. But as we all know, the road keeps going. Unless some a**hole blocks it."

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    MS is a serious health condition which affects both the brain and spinal cord. Symptoms of the condition include issues with vision, arm or leg movements, sensation or balance, muscle stiffness, numbness and problems with thinking, learning and planning.

    Applegate appeared on the Let's Talk Off Camera with Kelly Ripa podcast recently and said she had a conversation with her 14-year-old daughter Sadie about her health issues.

    The actor pictured with her 14-year-old daughter in 2023 (Emma McIntyre/FilmMagic)
    The actor pictured with her 14-year-old daughter in 2023 (Emma McIntyre/FilmMagic)

    In the honest chat, Applegate admitted: "I don't get up in the morning with that, I get up because of her. She's the reason I'm still here and trying."

    The actor added: "But she did say to me, and we got into a big thing the other day, and sorry Sadie, but it has to be said. She said, 'I missed who you were before you got sick'.

    "That is just like a knife to the heart because I miss who I was before I got sick too. Very much."

    Applegate has opened up on her daily struggles living with MS and the toll that has taken on her mental health.

    Speaking on an episode of her podcast MeSsy, Applegate said: "This is being really honest. I don't enjoy living. I don't enjoy it. I don't enjoy things anymore.

    "If someone's like, let's get up and go for a walk and or let's go get a coffee… I don't enjoy that process."

    Christina Applegate detailed her diagnosis in 2021 (Amy Sussman/WireImage)
    Christina Applegate detailed her diagnosis in 2021 (Amy Sussman/WireImage)

    She added: "What makes it harder is when you compare it to how it used to be. I'm in a depression right now, which I don't think I've felt that for, like, years.

    "Like a real f**k-it-all depression, like real depression, where it's kind of scaring me too a little bit, because it feels really fatalistic… I'm trapped in this darkness right now that I haven't felt like that in, I don't even know how long, probably 20-something years."

    Featured Image Credit: Gilbert Flores/Variety via Getty Images

    Topics: Celebrity, Christina Applegate, Film and TV, Health, Mental Health, Parenting

    Callum Jones
    Callum Jones

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    • Christina Applegate reveals how her MS diagnosis has ‘broken’ her 14-year-old daughter Sadie
    • Christina Applegate opens up on multiple sclerosis diagnosis reality as she reveals she's mostly confined to her bed
    • Christina Applegate details side effect of MS that stopped her from looking in the mirror for a year
    • Christina Applegate shares five ‘weird’ symptoms she ignored before MS diagnosis

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