• News
  • Film and TV
  • Music
  • Tech
  • Features
  • Celebrity
  • Politics
  • Weird
  • Community
  • Advertise
  • Terms
  • Privacy & Cookies
  • LADbible Group
  • LADbible
  • SPORTbible
  • GAMINGbible
  • Tyla
  • UNILAD Tech
  • FOODbible
  • License Our Content
  • About Us & Contact
  • Jobs
  • Latest
  • Topics A-Z
  • Authors
Facebook
Instagram
X
Threads
TikTok
YouTube
Submit Your Content
Doctor who took weight loss injections explains the uncomfortable side effect he suffered

Home> News> Health

Published 15:12 16 Jun 2025 GMT+1

Doctor who took weight loss injections explains the uncomfortable side effect he suffered

Dr. David A. Kessler put the GLP-1 jabs to the test

Liv Bridge

Liv Bridge

A doctor who tried weight loss injections has revealed the uncomfortable side effect he suffered.

Many GLP-1 drugs on the market are geared to help treat people with type two diabetes, supporting them to manage their blood sugar levels.

Yet while some are reserved for diabetic patients, types of GLP-1 drugs like Mounjaro have also been prescribed for people who are hoping to shed a few pounds as it works to suppress appetite.

However, that's not to say the drugs are completely risk-free as one doctor found out when he put the weight loss jabs to the test himself.

Advert

Dr David A. Kessler enjoyed a long career in public health, including almost a decade as Commissioner of the Food and Drug Administration in the 1990s and two years as chief science officer of the White House Covid-19 Response Team, but had battled with his weight since college.

There can be some serious side effects with the drugs (Getty Images)
There can be some serious side effects with the drugs (Getty Images)

The doc admits while he knows how to promote a healthy lifestyle, he didn't always practice what he preached in medical school, turning to French fries and salted roast beef to keep him studying throughout the night.

Kessler said he gained 20 or 40 pounds in a short time frame but slowly lost it, often by turning to an extreme low-carb, high-protein diet with regular exercise.

Advert

Yet it all crept back on and his prior regimen no longer worked - so he decided to put the new class of 'fat loss jabs' to the test.

In his new book Diet, Drugs, and Dopamine: The New Science of Achieving a Healthy Weight, the doctor revealed he shed a whopping 60 pounds within seven months of the injections, but has warned there was at least one uncomfortable side effect to the plan.

Speaking to NPR, he said GLP-1 drugs are great at teaching users how to eat, increasing the feeling of satiety and making you feel full after a small meal.

It can make patients feel uncomfortable as they re-learn how to eat (Getty Images)
It can make patients feel uncomfortable as they re-learn how to eat (Getty Images)

Advert

However, he said that feeling of fullness can be uncomfortable, describing it as like being 'at the edge of nausea.'

Pushing through the pain only makes matters worse, he continued, as users expose themselves to issues like abdominal pain, diarrhoea and vomiting or even hypoglycaemia which can require emergency hospital treatment.

But he suggests this is all a part of how it works, explaining further: "If you know that if you put anything else in that stomach that's going to cause distress, you become conditioned to not to put more food in your stomach."

Kessler also said he believes drugmakers and the FDA should educate consumers about the potential risks, adding: "I don't think the companies have leveled with the American public on how these drugs work."

Advert

"The companies and the FDA, no one's identified an endgame with these drugs," he continued, describing how there is little guidance available to help patients come off the drugs and maintain their new healthy weight.

Still, he says GLP-1 drugs for shredding off the pounds have 'changed the landscape of weight loss' and while they fall short at tackling the 'root cause' of obesity, they are 'effective tools' in the interim.

Featured Image Credit: Getty Images/The Washington Post

Topics: Health, US News, Fitness, Drugs

Liv Bridge
Liv Bridge

Liv Bridge is a digital journalist who joined the UNILAD team in 2024 after almost three years reporting local news for a Newsquest UK paper, The Oldham Times. She's passionate about health, housing, food and music, especially Oasis...

X

@livbridge

Advert

Advert

Advert

Choose your content:

6 hours ago
9 hours ago
10 hours ago
11 hours ago
  • 6 hours ago

    Amazon Prime series with near-perfect RT score is labeled 'one of the best' by Stephen King

    The series starring Titus Welliver has been branded 'one of the most underrated TV shows'

    Film & TV
  • 9 hours ago

    People horrified after hearing tech billionaire Peter Thiel’s ‘sociopathic’ response about the future of humanity

    People have been creeped out by how he answered a simple question

    News
  • 10 hours ago

    Doctor issues warning over hidden symptoms of Lyme disease as tick bites near record highs in US states

    Parts of the US have seen a sudden uptick in tick bites

    News
  • 11 hours ago

    ‘World’s top couple’s therapist’ reveals the one surprising behavior in people’s relationships that ‘scares her’

    The psychologist said this one thing in other couples doesn't seem real

    News
  • Health experts warn of disturbing potential side effect of weight loss jabs after 10 people die
  • Two best friends who took 'weight loss drug' at the same time reveal the shocking results
  • Wegovy study labeled medical breakthrough in fighting key side effect of weight loss medication
  • Macy Gray shares harsh Ozempic side effect that kept her 'up all night'