• News
  • Film and TV
  • Music
  • Tech
  • Features
  • Celebrity
  • Politics
  • Weird
  • Community
  • Advertise
  • Terms
  • Privacy & Cookies
  • LADbible Group
  • LADbible
  • SPORTbible
  • GAMINGbible
  • Tyla
  • UNILAD Tech
  • FOODbible
  • License Our Content
  • About Us & Contact
  • Jobs
  • Latest
  • Topics A-Z
  • Authors
Facebook
Instagram
X
Threads
TikTok
YouTube
Submit Your Content
Scientists have discovered an early warning sign of Alzheimer's visible in routine scans

Home> News> Health

Published 16:26 10 Dec 2025 GMT

Scientists have discovered an early warning sign of Alzheimer's visible in routine scans

Progression of the disease could be slowed thanks to the breakthrough

Ellie Kemp

Ellie Kemp

google discoverFollow us on Google Discover
Featured Image Credit: Teera Konakan/Getty Images

Topics: Dementia, Health, World News, Science, US News

Ellie Kemp
Ellie Kemp

Ellie joined UNILAD in 2024, specialising in SEO and trending content. She moved from Reach PLC where she worked as a senior journalist at the UK’s largest regional news title, the Manchester Evening News. She also covered TV and entertainment for national brands including the Mirror, Star and Express. In her spare time, Ellie enjoys watching true crime documentaries and curating the perfect Spotify playlist.

X

@EllieKempOnline

Advert

Advert

Advert

An 'early warning sign' of dementia that can be picked up during routine health scans has been identified.

The degenerative brain condition is estimated to impact more than 55 million people worldwide.

Alzheimer's is the most common form of dementia and sadly, cases are on the rise.

In the US, some 13 million people are estimated to have the disease by 2050, as per the Alzheimer's Association.

Advert

While lifestyle habits like eating certain foods and walking daily are said to help 'prevent' Alzheimer's, some people are more genetically predisposed to the condition.

Alzheimer's is caused by the abnormal build-up of plaques and tangles in the brain, which causes cells to die and the brain to shrink over time.

More than six million Americans live with dementia (Brizmaker/Getty Images)
More than six million Americans live with dementia (Brizmaker/Getty Images)

Early symptoms of Alzheimer's disease include forgetting recent events or conversations.

Over time, it can lead to serious memory loss and impact a person's ability to do everyday tasks, the Mayo Clinic says.

Now, scientists from from Nanyang Technological University in Singapore have made a breakthrough.

They've discovered that clogged drainage spaces on the brain, visible on scans, can be linked with early signs of dementia.

In fact, people with early cognitive issues, like mild memory problems, are more likely to have these clogged spaces.

These drains help remove toxic waste from the organ but can become enlarged when backed up.

Known as enlarged perivascular spaces, they are visible on routine Magnetic Resonance Imaging (MRI) scans.

The warning sign was picked up on routine MRI scans (Luis Alvarez/Getty Images)
The warning sign was picked up on routine MRI scans (Luis Alvarez/Getty Images)

Some 40 million MRI scans are performed annually in the US each year.

These enlarged spaces can be linked to other signs of Alzheimer’s, including higher amyloid plaques, more tau tangles and signs of brain cell damage.

This suggests the clogging happens before major brain damage, making it a promising early detection marker.

“Since these brain anomalies can be visually identified on routine magnetic resonance imaging (MRI) scans performed to evaluate cognitive decline, identifying them could complement existing methods to detect Alzheimer’s earlier, without having to do and pay for additional tests,” said Associate Professor Nagaendran Kandiah, who led the study.

Almost 1,000 participants in Singapore were studied, including nearly 350 who did not have any cognitive issues.

A patient who with enlarged perivascular spaces, as seen on an MRI scan (NTU LKCMedicine)
A patient who with enlarged perivascular spaces, as seen on an MRI scan (NTU LKCMedicine)

Fifth year medical student and first author of the study, Justin Ong, added that spotting Alzheimer’s at an earlier stage allows doctors to intervene sooner.

This means they could potentially slow the progression of symptoms such as memory loss, reduced processing speed and mood changes, Sci Tech Daily notes.

The study's findings were published in the Neurology Journals in September.

If you've been affected by dementia or Alzheimer's and would like to speak with someone in confidence, contact the Alzheimer's Association via 800.272.3900 open 24 hours seven days a week.

  • Early warning sign of dementia may be visible through your bank account, study finds
  • Mom, 47, diagnosed with early-onset Alzheimer's disease reveals the first symptoms she noticed
  • Experts issue urgent warning about the little-known signs of early dementia which have nothing to do with memory
  • Scientists present new possible cause of Parkinson's disease and explain surge in diagnosis

Choose your content:

an hour ago
2 hours ago
7 hours ago
8 hours ago
  • Tang Xinyu/VCG via Getty Images
    an hour ago

    Alysa Liu slams Eileen Gu’s ‘hypocritical’ critics as she defends fellow Olympian for representing China

    The Olympic champion argued: 'There's no shame in going where the opportunity is'

    Celebrity
  • Harold Cunningham / Getty Images
    2 hours ago

    Six dead and five injured in 'deliberate' Swiss bus fire

    It marks the second deadly fire to rock Switzerland since the start of the year.

    News
  • Getty Stock
    7 hours ago

    Scientists reveal how much sleep is too much and how to achieve the perfect amount

    We're often told about getting the eight hours of kip...

    News
  • Monica Schipper/Getty Images for The Recording Academy
    8 hours ago

    Paul McCartney claims Yoko Ono ‘believed John Lennon might have been gay’

    Claims that The Beatles' singer-songwriter John Lennon may have slept with men were repeated by Paul McCartney in an unearthed interview

    Music