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Kidney disease explained as New York Jets legend Nick Mangold dies of complications aged 41

Home> News> Health

Updated 12:06 27 Oct 2025 GMTPublished 11:55 27 Oct 2025 GMT

Kidney disease explained as New York Jets legend Nick Mangold dies of complications aged 41

One in seven American adults are impacted by the condition

Ellie Kemp

Ellie Kemp

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Featured Image Credit: Getty Images/George Gojkovich

Topics: Health, NFL, US News

Ellie Kemp
Ellie Kemp

Ellie joined UNILAD in 2024, specialising in SEO and trending content. She moved from Reach PLC where she worked as a senior journalist at the UK’s largest regional news title, the Manchester Evening News. She also covered TV and entertainment for national brands including the Mirror, Star and Express. In her spare time, Ellie enjoys watching true crime documentaries and curating the perfect Spotify playlist.

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Former New York Jets star Nick Mangold has died following complications from chronic kidney disease aged 41.

The football center heartbreakingly admitted he thought he 'would have had more time' weeks before his death.

More than 35 million US adults are affected by chronic kidney disease, as per the National Institute of Health. That's roughly one in seven adults.

Mangold, considered one of the most beloved figures in Jets history, died on Sunday (October 26), the Jets confirmed. The former NFL star had taken to X, formerly Twitter, weeks prior for an update on his health.

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He explained that in 2006, he had been diagnosed with a genetic defect that led to chronic kidney disease - a gradual loss of kidney function.

"After a rough summer, I'm undergoing dialysis as we look for a kidney transplant," he added.

New York Jets Legend Nick Mangold pictured speaking to the press last year (Jared Silber/NHLI via Getty Images)
New York Jets Legend Nick Mangold pictured speaking to the press last year (Jared Silber/NHLI via Getty Images)

"I always knew this day would come, but I thought I would have had more time."

Mangold went on to explain that none of his family were able to donate kidneys as he appealed to the NY Jets and Ohio State communities for help finding a potential match.

His post continued: "Most of all, I'm thankful for my family, who have been my rock every step of the way. This situation has reminded me how lucky I am to have such an amazing family, friends, and community behind me."

Symptoms of chronic kidney disease

Around one in seven US adults have chronic kidney disease (Peterschreiber.media/Getty Images)
Around one in seven US adults have chronic kidney disease (Peterschreiber.media/Getty Images)

According to Mayo Clinic, kidney damage progresses slowly, with symptoms developing over time.

"Loss of kidney function can cause a buildup of fluid or body waste or electrolyte problems," it adds.

Depending on the severity of the condition, other symptoms include:

  • Nausea
  • Vomiting
  • Loss of appetite
  • Fatigue and weakness
  • Sleep problems
  • Urinating more or less
  • Decreased mental sharpness
  • Muscle cramps
  • Swelling of feet and ankles
  • Dry, itchy skin
  • High blood pressure that's difficult to manage
  • Shortness of breath, from fluid building up in the lungs
  • Chest pain, from fluid building up around the lining of the heart

The Mayo Clinic adds that chronic kidney disease can impact 'almost every part' of the body, running the risk of complications.

Possible complications include fluid retention, high blood pressure, pulmonary edema, and hyperkalemia, which can affect heart function.

Other effects include anemia, heart disease, weak bones, reduced fertility or sex drive and nervous system issues like confusion or seizures.

The immune system may weaken, increasing infection risk.

Additional complications include pericarditis, pregnancy risks for mother and fetus, and irreversible kidney failure requiring dialysis or transplant.

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