Medics are studying a rare illness that seemingly makes people 'allergic' to their own orgasms after a man presented to them with bizarre symptoms.
There are some pretty unusual health conditions and problems out there, including a man getting food poisoning in his penis in what appears to be world-first case.
But now, a new case study has revealed a man is essentially 'allergic to his own orgasms' after scientists looked further into the source of his rather unusual health ailment.
What is post-orgasmic illness syndrome (POIS)?
The 22-year-old, who is from Israel, has a condition known as post-orgasmic illness syndrome (POIS), which is said to be caused by an allergic reaction to a protein released by the immune system once a male reaches climax.
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Some of the symptoms the unidentified man has experienced since the age of 14 include fatigue, muscle pain and watery eyes.
The uncomfortable symptoms would occur after sex, masturbation or even after wet dreams - meaning the Israeli man sometimes had no control over when the symptoms would present themselves.
POIS is incredibly rare, with reports suggesting is affects just 50 people worldwide, meaning the man was left extremely perplexed by his ongoing symptoms.
And after the illness made it impossible for him to hold down a relationship, on top of symptoms of depression and anxiety for a number of years, the young man decided to take himself to the doctor.
Potential POIS treatment
After receiving a diagnosis, things are seemingly on the up for the man after medics appear to have had a breakthrough in treating the rare condition.
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Doctors prescribed the man omalizumab, which is injected under the skin and is typically prescribed to patients suffering from chronic hives, allergies, and asthma.
However, using the treatment for POIS, which was only discovered 20 years ago, is a last resort and means the man has to inject himself every time he, erm, gets it on.
A study published in the American Journal of Case Reports explains: "Omalizumab may be considered for the treatment of POIS in patients with allergy-like symptoms and symptoms that cannot be controlled with other medications, even in the absence of a positive skin test to semen. Lower doses may be ineffective."
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And it appears to have been a success - according to the study, seven months of taking the injection have gotten rid of his symptoms altogether.
He was eventually able to have sex and masturbate normally, with the study revealing: "Currently, while on omalizumab, the patient is symptom-free and feels comfortable engaging in sexual activity."
Callum Jones