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Having faced off in the ring on more than one occasion, their careers have taken similar paths, with Cena looking to follow in Dwayne Johnson's footsteps on the acting front.
Some might argue that Johnson's transition from wrestling to acting has paved the way for the likes of Cena to progress into the new field.
However, the 16-time world champion has now revealed how grateful he is for Johnson's advice when starting out in Hollywood.
At a Comic-Con Wales Q&A session, Cena was asked if 'The People's Champ' gave him any advice before getting into movies.
To which Cena replied: "I was able to ask him, 'Hey man, do you have any advice?'
"He said, 'They asked you there for a reason dude; just be yourself'.
"He, in that one sentence, allowed me to calm down.
"Allowed me to be myself, which I'm really a goofball.
"And [the movie Trainwreck] allowed me to do that on screen. Naked.
"He's the reason I'm here."
Cena also revealed that he will return to WWE despite not being sure if he'll break Ric Flair's world title record, which varies by source, but it said to be around the 21-title region.
He said: "That's a very difficult question. Like I said, I know I'm not done in the ring.
"But I am realistic with where I'm at in my life. I'm 45 and I can tell you from being a 16-time champion, it is very tough to win.
"The top of that mountain is a young man's game. So I'm not done in the ring, but I'm not certain that that's in the cards. We'll see.
"[There are] stories yet to be told, because if I'm in the ring, I got a chance. I am just saying I've been there, so kudos to the young guys doing it."
When asked what his favourite match of his career is, the 45-year-old added: "My answer is always the same. My next one.
"I haven’t yet hit the point where I’m fully retired, so I can always say my next one.
"Someday, I’ll have to reflect back and pick a favourite, but I know I’m not done with the ring, so my next one is my favourite one."
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